Skip to main content
. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Expert Rev Anticancer Ther. 2009 Jun;9(6):785–793. doi: 10.1586/era.09.43

Table 2.

Summary of MET tyrosine kinase domain mutations.

Swissprot Genbank Germline/somatic Ref.
H1094R H1112R Germline [39]
M1131T M1149T Germline [123]
V1188L V1206L Germline [26]
L1195V L1213V Somatic [26]
D1228N D1246N Germline [26]
D1228H D1246H Somatic [26]
Y1230C Y1248C Germline [26]
Y1230H Y1248H Somatic [26]
Y1235D Y1253D Somatic [124,125]
M1250T M1268T Somatic [26]

Mutations are listed by codon position in SwissProt (accession P08581) or Genbank (accession J02958) sequence contexts.