TABLE 2.
Normotensives by Quartile of Renin Activity
| Quartiles of Plasma Renin Activity (range: ng/mL per hour) | |||||
|---|---|---|---|---|---|
| Parameter | 1 (0.2–0.6) | 2 (0.6–1.0) | 3 (1.1–1.8) | 4 (2.0–12.5) | P |
| No. | 22 | 22 | 22 | 21 | |
| Age (y) | 39±13 | 39±14 | 34±13 | 39±13 | 0.59 |
| BMI (kg/m2) | 27±5 | 27±5 | 25±4 | 26±5 | 0.53 |
| Female, n (%) | 9 (41) | 8 (36) | 10 (45) | 7 (33) | 0.86 |
| Black, n (%) | 15 (68) | 11 (50) | 8 (36) | 9 (43) | 0.18 |
| Systolic BP (mm Hg) | 129±15 | 122±12 | 118±11 | 119±11 | 0.02 |
| Diastolic BP (mm Hg) | 79±10 | 76±10 | 74±9 | 70±10 | 0.04 |
| Total cholesterol (mg/dL) | 165±34 | 170±31 | 178±35 | 184±32 | 0.24 |
| LDL (mg/dL) | 96±28 | 105±27 | 104±30 | 116±30 | 0.16 |
| HDL (mg/dL) | 50±17 | 47±12 | 54±17 | 50±14 | 0.52 |
| Triglycerides (mg/dL) | 96±61 | 91±51 | 106±81 | 92±47 | 0.85 |
| Glucose (mg/dL) | 101±17 | 93±15 | 101±28 | 98±16 | 0.47 |
| Creatinine (mg/dL) | 0.83±0.20 | 0.77±0.22 | 0.80±0.21 | 0.75±0.14 | 0.55 |
| Renin (ng/mL per hour) | 0.39±0.13 | 0.78±0.15 | 1.35±0.25 | 3.75±2.52 | <0.001 |
| Aldosterone (ng/dL) | 7.8±6.4 | 7.4±2.6 | 6.6±2.3 | 12.3±6.5 | 0.001 |
| Aldosterone/renin | 23.9±27.6 | 9.7±3.6 | 5.0±2.0 | 4.1±2.9 | <0.001 |
Data are mean±SD. P value refers to overall ANOVA.