Table 3.
Association between MetS components in quartiles and metachronous neoplasia in men (n = 1,609)
| Any metachronous neoplasia (n = 800) |
Nonadvanced neoplasia (n = 563) |
Advanced neoplasia (n = 236) |
Single metachronous neoplasia (n = 382) |
Multiple metachronous neoplasia (n = 418) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| % | OR* (95% CI) | % | OR† (95% CI) | % | OR† (95% CI) | % | OR† (95% CI) | % | OR† (95% CI) | |
| Waist circumference (inches) | ||||||||||
| 34.6 ± 1.6 | 44.7 | 1.00 | 31.1 | 1.00 | 13.6 | 1.00 | 20.5 | 1.00 | 24.2 | 1.00 |
| 37.8 ± 0.7 | 47.4 | 1.13 (0.85–1.50) | 34.8 | 1.19 (0.88–1.62) | 12.5 | 0.97 (0.63–1.49) | 24.9 | 1.28 (0.91–1.81) | 22.4 | 1.00 (0.70–1.42) |
| 40.5 ± 0.9 | 52.4 | 1.36 (1.03–1.80) | 35.1 | 1.33 (0.98–1.81) | 17.2 | 1.44 (0.96–2.15) | 24.5 | 1.38 (0.98–1.96) | 27.8 | 1.35 (0.97–1.89) |
| 45.4 ± 2.9 | 54.6 | 1.61 (1.21–2.14) | 39.3 | 1.67 (1.22–2.28) | 15.3 | 1.48 (0.97–2.26) | 25.1 | 1.53 (1.07–2.19) | 29.6 | 1.69 (1.20–2.39) |
| Triglycerides (mg/dL) | ||||||||||
| 75.1 ± 14.8 | 48.2 | 1.00 | 32.4 | 1.00 | 15.7 | 1.00 | 21.4 | 1.00 | 26.8 | 1.00 |
| 114.8 ± 11.3 | 51.3 | 1.12 (0.84–1.48) | 36.9 | 1.19 (0.87–1.62) | 14.3 | 0.96 (0.64–1.45) | 26.1 | 1.29 (0.91–1.83) | 25.1 | 0.97 (0.69–1.36) |
| 162.8 ± 17.8 | 49.9 | 1.06 (0.80–1.40) | 34.7 | 1.08 (0.79–1.47) | 15.1 | 1.01 (0.67–1.51) | 24.9 | 1.20 (0.85–1.70) | 24.9 | 0.95 (0.67–1.33) |
| 296.6 ± 108.1 | 49.6 | 1.08 (0.82–1.43) | 36.1 | 1.15 (0.85–1.57) | 13.5 | 0.94 (0.62–1.42) | 22.6 | 1.10 (0.77–1.56) | 27.1 | 1.08 (0.77–1.51) |
| HDL (mg/dL) | ||||||||||
| 33.6 ± 3.9 | 47.8 | 1.00 | 34.7 | 1.00 | 13.1 | 1.00 | 23.7 | 1.00 | 24.1 | 1.00 |
| 41.9 ± 1.9 | 49.1 | 1.06 (0.80–1.40) | 33.9 | 1.01 (0.74–1.37) | 15.0 | 1.18 (0.77–1.79) | 24.7 | 1.07 (0.76–1.50) | 24.4 | 1.05 (0.74–1.48) |
| 49.1 ± 2.3 | 51.3 | 1.12 (0.85–1.47) | 37.0 | 1.11 (0.82–1.50) | 14.3 | 1.13 (0.74–1.72) | 23.2 | 1.04 (0.73–1.46) | 28.1 | 1.20 (0.85–1.68) |
| 64.9 ± 11.6 | 50.9 | 1.06 (0.81–1.40) | 34.5 | 1.00 (0.74–1.35) | 16.4 | 1.25 (0.83–1.87) | 23.5 | 1.03 (0.73–1.44) | 27.4 | 1.10 (0.79–1.54) |
| Systolic blood pressure (mm Hg) | ||||||||||
| 109.7 ± 6.2 | 47.5 | 1.00 | 32.6 | 1.00 | 14.8 | 1.00 | 25.5 | 1.00 | 22.0 | 1.00 |
| 122.9 ± 2.9 | 49.7 | 1.06 (0.79–1.41) | 34.3 | 1.07 (0.77–1.47) | 15.4 | 1.03 (0.67–1.57) | 23.0 | 0.93 (0.65–1.32) | 26.8 | 1.22 (0.85–1.75) |
| 134.9 ± 4.2 | 49.4 | 1.00 (0.75–1.31) | 34.7 | 1.04 (0.77–1.41) | 14.6 | 0.88 (0.59–1.33) | 20.9 | 0.82 (0.58–1.16) | 28.4 | 1.20 (0.86–1.69) |
| 154.7 ± 10.4 | 52.3 | 1.06 (0.79–1.42) | 38.3 | 1.17 (0.85–1.62) | 14.0 | 0.82 (0.53–1.26) | 26.1 | 1.06 (0.75–1.51) | 26.1 | 1.07 (0.75–1.54) |
| Diastolic blood pressure (mm Hg) | ||||||||||
| 65.9 ± 5.1 | 47.7 | 1.00 | 33.2 | 1.00 | 14.6 | 1.00 | 23.5 | 1.00 | 24.3 | 1.00 |
| 75.5 ± 2.2 | 52.0 | 1.30 (0.96–1.78) | 38.1 | 1.37 (0.98–1.92) | 13.9 | 1.16 (0.73–1.84) | 23.5 | 1.14 (0.77–1.67) | 28.5 | 1.48 (1.02–2.16) |
| 81.2 ± 1.6 | 50.7 | 1.26 (0.96–1.65) | 35.4 | 1.24 (0.92–1.68) | 15.2 | 1.28 (0.86–1.91) | 24.4 | 1.16 (0.83–1.61) | 26.3 | 1.37 (0.99–1.91) |
| 91.8 ± 5.9 | 48.5 | 1.19 (0.89–1.60) | 33.8 | 1.18 (0.85–1.62) | 14.7 | 1.25 (0.81–1.92) | 23.2 | 1.07 (0.75–1.53) | 25.3 | 1.33 (0.93–1.91) |
| Fasting glucose (mg/dL) | ||||||||||
| 89.8 ± 5.8 | 47.6 | 1.00 | 32.7 | 1.00 | 14.9 | 1.00 | 23.2 | 1.00 | 24.4 | 1.00 |
| 98.9 ± 1.9 | 49.4 | 1.11 (0.85–1.46) | 34.9 | 1.15 (0.85–1.55) | 14.5 | 1.03 (0.69–1.55) | 24.1 | 1.09 (0.78–1.52) | 25.3 | 1.13 (0.81–1.58) |
| 106.6 ± 2.7 | 48.3 | 1.04 (0.78–1.37) | 34.2 | 1.08 (0.79–1.48) | 14.0 | 0.94 (0.62–1.43) | 22.6 | 0.99 (0.70–1.41) | 25.6 | 1.08 (0.76–1.53) |
| 140.0 ± 37.9 | 53.7 | 1.28 (0.97–1.69) | 38.4 | 1.34 (0.99–1.83) | 15.2 | 1.12 (0.74–1.69) | 24.9 | 1.21 (0.86–1.71) | 28.8 | 1.35 (0.96–1.89) |
*
OR from logistic regression adjusted for age and study.
†
OR from multinomial logistic regression adjusted for age and study.