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. Author manuscript; available in PMC: 2010 Aug 7.
Published in final edited form as: J Theor Biol. 2009 Apr 5;259(3):469–477. doi: 10.1016/j.jtbi.2009.03.030

Table 1.

Isoboles shapes for special cases of combinations of agents described by Hillfunctions with slope parameter of one

Case Slopes of isoboles*
Concentration addition Negative, not necessarily equal
TEFs Negative and equal
Competitive antagonism Positive
Partial agonist Negative below maximal effect level of partial agonist; positive above
*

All isoboles are linear.