Table 1.
GCH-1 interactome identified by LC/MS/MS.
| Protein Names | Accession | Scan count | Protein function |
|---|---|---|---|
| N-acetyltransferase-like protein | Q9H0A0 | 47 | Histone acetyltransferase |
| Protein FAM21C | Q9Y4E1 | 32 | Unknown |
| Thyrotropin-releasing hormone degrading ectoenzyme | Q9UKU6 | 29 | Inactivation of TRH |
| Molecule interacting with CasL protein 1 | Q8TDZ2 | 17 | Cytoskeletal regulator |
| Rho-GTPase-activating protein 7 | Q96QB1 | 16 | Cytoskeletal reorganization |
| NKG2-A/B-activating NK receptor | P26715 | 15 | Receptor fo rMHC recognition |
| Proprotein convertase subtilisin/kexin type 9 | Q8NBP7 | 15 | Dfferentiation of cortical neurons |
| Spectrin beta chain, brain 3 | Q9H254 | 13 | Cytoskeletal anchoring |
| Maspin precursor | P36952 | 11 | Tumor suppressor |
| Death-associated protein kinase 3 | O43293 | 10 | Regulator of apoptosis |
| Peroxisome assembly protein 12 | O00623 | 10 | Import into peroxisomes |
| Protocadherin 15 precursor | Q96QU1 | 9 | Cell-adhesion |
| USP6 N-terminal-like protein | Q92738 | 9 | Receptor trafficking |
| Apoptosis inhibitor 5 | Q9BZZ5 | 9 | Antiapoptotic factor |
| Centromere protein H | Q9H3R5 | 8 | Assembly of kinetochore |
| CENP-F kinetochore protein | P49454 | 7 | Chromosome segregation |
| Separin | Q14674 | 7 | Caspase-like protease |
| Latrophilin-2 precursor | O95490 | 6 | Regulation of exocytosis |
| Cyclic AMP-dependent transcription factor ATF-6 alpha | P18850 | 5 | Transcription factor |
| Huntingtin-interacting protein 1-related protein | O75146 | 5 | Component of clathrin-coated pits |
| Polyribonucleotide nucleotidyl-transferase | Q8TCS8 | 5 | mRNA degradation |
| Rho guanine nucleotide exchange factor 3 | Q9NR81 | 5 | GEF for Rho GTPase |
| Baculoviral IAP repeat-containing protein 3 | Q13489 | 4 | Apoptotic suppressor |
| Centromeric protein E | Q02224 | 4 | Microtubule motor |
| Splicing factor 3A subunit 3 | Q12874 | 4 | ‘A’ complex assembly |
| Afamin precursor | P43652 | 4 | Transport |
| Histone H2B | P62807 | 4 | Component of nucleosome |
| Interferon regulatory factor 1 | P10914 | 4 | Transcription factor |
| Proteoglycan-4 precursor | Q92954 | 4 | Boundary lubrication |