Table I.
WT | WT/WT | WT/KO | KO/WT | KO + rmIL-6 | WT/WT/WT | WT/KO/WT | |
---|---|---|---|---|---|---|---|
Mean (95% CI) (pg/ml) | 3034 (2008) | 1222 (597) | 1590 (952) | 156b (83) | 3277 (3183) | 2558 (2216) | 1577 (1204) |
N = 6–9 mice in each group. WT, WT C57BL/6 mice; WT/WT, WT mice irradiated and reconstituted with bone marrow from WT mice; WT/KO, WT mice irradiated and reconstituted with bone marrow from IL6KO mice; KO/WT, IL6KO mice irradiated and reconstituted with bone marrow from WT mice; KO + rmIL-6, IL6KO mice pretreated with rmIL-6; WT/WT/WT, WT/WT mice given WT neutrophils immediately before mechanical ventilation; and WT/KO/WT, WT/KO mice given WT neutrophils immediately before mechanical ventilation.
p < 0.05 compared with WT/WT and WT/KO.