Table 4.
Parametric Effects of WM-load: Conjunction Controls and Pre-Treatment OSA Patients
| H | Anatomical region (BA) Controls and Pre-treatment OSA | ATp | K | Cluster labeling | MNI |
Z-score | ||
|---|---|---|---|---|---|---|---|---|
| x | y | z | ||||||
| L | Superior parietal lobule (7) | 46 | −24 | −76 | 46 | 5.87 | ||
| Inferior parietal lobule (7) | −32 | −70 | 44 | 5.29 | ||||
| L | Superior parietal lobule (7/39) | 13 | −36 | −62 | 48 | 5.57 | ||
| L | Inferior parietal lobule (40) | 108 | 26.9% in L hIP1 | −34 | −50 | 44 | 6.46 | |
| Inferior parietal lobule (hIP1*) | 50* | 13.8% in L hIP2 | −40 | −48 | 46 | 5.63 | ||
| Inferior parietal lobule (hIP2*) | 60* | −48 | −44 | 44 | 5.24 | |||
| R | Superior occipital gyrus (7) | 9 | 32 | −68 | 42 | 5.42 | ||
| R | Inferior parietal lobule (hIP1*) | 40* | 129 | 19.9% in R hIP1 | 38 | −46 | 40 | 6.44 |
| Inferior parietal lobule (40) | 10.4% in R hIP2 | 50 | −50 | 46 | 6.28 | |||
| L/R | SMA (6*) | 20* | 46 | 41.3% in L area 6 | −2 | 12 | 50 | 5.62 |
| SMA (6/32) | 13.6% in R area 6 | 4 | 20 | 48 | 5.43 | |||
| L | Precentral gyrus (6) | 30 | 4 | −44 | 2 | 46 | 5.19 | |
| L | Middle frontal gyrus (44/45) | 40* | 11 | 34.1% in L area 45 | −46 | 22 | 30 | 5.35 |
| IFG pars triangularis (45*/45) | 29.5% in L area 44 | |||||||
| L | Insula lobe | 48 | −30 | 22 | 0 | 6.43 | ||
| R | Insula lobe | 42 | 34 | 22 | −2 | 5.81 | ||
| IFG pars orbitalis (47) | 32 | 26 | −6 | 5.75 | ||||
| L | Cerebellum (Crus1) | 71 | −28 | −66 | −32 | 6.50 | ||
| L | Cerebellum (Crus 1) | 6 | −16 | −76 | −30 | 5.16 | ||
| R | Cerebellum (Crus 1) | 171 | 32 | −66 | −32 | 6.33 | ||
| R | Cerebellum (Crus 1) | 25 | 12 | −78 | −28 | 5.37 | ||
| Cerebellum (Crus 2) | 6 | −86 | −32 | 5.52 | ||||
| L | Thalamus | 8 | −16 | −28 | 14 | 5.41 | ||
Regions showing a significant linear increase of cerebral activation related to WM load in both controls and pretreatment OSA patients (P < 0.05 FWE corrected for multiple comparisons, minimum cluster size K = 4 voxels). H = Hemisphere, L = Left, R = Right, BA = estimated Brodmann area, ATp = most probable anatomical regions (where available) in the Anatomy toolbox [Eickhoff et al., 2005; asterisks denote assignment], K = cluster-extension in number of voxels (2 × 2 × 2 mm3), hIP = human Intra-Parietal area, SMA = supplementary motor area, IFG = inferior frontal gyrus.