Table 5.

Differential parametric effects of WM load in controls and pretreatment OSA patients

H	Anatomical region (BA)	ATp	K	Cluster labeling	MNI			Z-score
					x	y	z
	a. Controls > Pretreatment OSA,Inclusively masked by Conj
	No significant clusters
	b. Controls > Pretreatment OSA, Exclusively masked by Conj
L/R	Brainstem		27		2	−28	−36	3.40
	Brainstem				−4	−28	−32	3.30
L	Middle occipital gyrus (19)		19		−28	−68	30	3.30
R	Middle orbital gyrus (47/46)		11		38	50	−8	3.34
	c. Pretreatment OSA > Controls, Inclusively masked by Conj
L	Precuneus (7)		61		−4	−66	52	4.14
L	IFG pars triangularis (45*/44)	40*/30	4	37.5% in L area 44	−50	16	2	3.59
L	Putamen		19		−20	2	6	4.03
	d. Pretreatment OSA > Controls, Exclusively masked by Conj
L/R	Precuneus (7)		33		−6	−66	52	3.95
L	Superior frontal gyrus (8/6)		59		−18	22	54	4.21
	Middle frontal gyrus (8)				−26	22	56	3.46
L	Middle frontal gyrus (44/46)		6		−36	20	34	3.41
L	IFG pars triangularis (45/44)	30/20	40	25.5% in L area 44	−48	18	2	3.98
				10.2% in L area 45
L	Superior frontal gyrus (10)		18		−20	62	12	4.07
L	Hippocampus	40*	10	16.7% in L hippocampus	−38	−18	−14	3.35
L	Cerebellum (IV-V)		21		−8	−50	−8	3.57

From top to bottom, cerebral regions showing significantly different parametric effects of WM-load in controls vs. pretreatment OSA within, and outside, the commonly activated regions (a and b, respectively), and in pretreatment OSA vs. controls within, and outside, the commonly activated regions (c and d, respectively) (P < 0.001 uncorrected for multiple comparisons, minimum cluster size K = 4 voxels). H = Hemisphere, L = Left, R = Right, BA = estimated Brodmann area, ATp = most probable anatomical regions (where available) in the Anatomy toolbox [Eickhoff et al., 2005; asterisks denote assignment], K = cluster-extension in number of voxels (2 × 2 × 2 mm³), IFG = inferior frontal gyrus.