Table I.
Effect of GalXM and GalXM-PA Conjugate on Antibody Titers 1
| GalXM (ug) | Titers Day 14 | Titers Day 28 | GalXM-PA Conjugate (ul) | Titers Day 14 | Titers Day 28 | ||
|---|---|---|---|---|---|---|---|
| n=3 | 6–8 weeks | 52 weeks | 6–8 weeks | 52 weeks | 6–8 weeks | 6–8 weeks | |
| 0.5 | 1/300 | 1/900 | 1/100 | 1/100 | 50 | 1/900 | 1/8100 |
| 5.0 | 1/900 | 1/2700 | 1/100 | 1/300 | 50 | 1/900 | 1/2700 |
| 50 | 1/900 | 1/900 | 1/100 | 1/100 | 100 | 1/2700 | 1/8100 |
| 500 | 1/900 | 1/2700 | 1/100 | 1/100 | CFA | 1/100 | 1/100 |
| CFA | 1/100 | 1/300 | 1/100 | 1/100 | PBS | 1/100 | 1/100 |
| PBS | 1/100 | 1/300 | 1/100 | 1/100 | BSA | 1/100 | 1/100 |
| BSA | 1/100 | 1/300 | 1/100 | 1/100 | |||
1
Fourteen days after initial immunization antibody response was measured using ELISA. After subsequent challenge with 0.1 μg of GalXM or the same initial dose of the conjugate, titers were evaluated at day 28. n = 3 mice per group for GalXM injected mice.