Table 2.

  Hazard ratios (95% confidence intervals) for associations between thigh circumference and total mortality for 1436 men aged 35-65 followed for 12.5 years

Centile of thigh circumference (cm)	Model 1*	Model 2†	Model 3‡	Model 4¶
2.5 (46.5)	1.59 (1.11 to 2.28)	2.62 (1.83 to 3.76)	2.53 (1.74 to 3.69)	2.23 (1.47 to 3.39)
5 (48.0)	1.38 (1.05 to 1.82)	2.14 (1.63 to 2.81)	2.11 (1.54 to 2.89)	1.90 (1.35 to 2.67)
10 (49.5)	1.21 (0.98 to 1.50)	1.75 (1.42 to 2.17)	1.76 (1.34 to 2.32)	1.61 (1.21 to 2.15)
25 (52.0)	1.02 (0.86 to 1.21)	1.30 (1.09 to 1.53)	1.32 (1.07 to 1.64)	1.26 (1.01 to 1.57)
50 (55.0)	1	1	1	1
75 (58.0)	1.09 (0.91 to 1.29)	0.84 (0.71 to 1.00)	0.81 (0.66 to 1.01)	0.83 (0.67 to 1.04)
90 (61.0)	1.14 (0.86 to 1.51)	0.73 (0.55 to 0.97)	0.70 (0.48 to 1.03)	0.70 (0.46 to 1.06)
95 (63.0)	1.16 (0.75 to 1.79)	0.67 (0.43 to 1.03)	0.64 (0.36 to 1.14)	0.62 (0.33 to 1.16)
97.5 (64.0)	1.17 (0.69 to 1.98)	0.64 (0.38 to 1.08)	0.62 (0.31 to 1.23)	0.58 (0.28 to 1.24)

*Adjusted for smoking, physical activity, and education.

†Additionally to * adjusted for body fat percentage and body height. P<0.001, likelihood ratio test for effect.

‡Additionally to * adjusted for BMI (body mass index) and waist circumference. P<0.001, likelihood ratio test for effect.

¶Additionally to ‡ adjusted for alcohol, systolic blood pressure, total cholesterol, and triglycerides. P<0.01, likelihood ratio test for effect.