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. 2009 Apr 20;13(5):866–886. doi: 10.1111/j.1582-4934.2009.00758.x

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© 2009 The Authors Journal compilation © 2009 Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd

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(A)–(C). Digitally coloured electron micrographs show cardiomyocyte progenitors (CMP, brown) in different stages of development and ICLC (blue). CMP have features of immature cardiomyocytes: a high nucleo-cytoplasmatic ratio and a continuous basal lamina (small arrows), numerous mitochondria (m) and ribosomes, few endoplasmic reticulum cisternae, some lipid droplets (l) and caveolae (*). These cells contain unorganized bundles of filaments (#) attached to electron dense structures (double arrows) similar to Z bands. (A) – ICLC processes (ICLCp) closely accompany the immature cardiomyocyte. B– The basal lamina exceeds the cellular profile and delimitates a slender acellular space. An ICLC process seems to support and direct this lamina (red dotted arrow). The large arrow indicates a gap junction in between two ICLCp. (C) – Note the presence of the subplasmalemmal leptofibrils (large arrows) and intracellular desmosome-like structures (arrowheads).

(A)–(C). Digitally coloured electron micrographs show cardiomyocyte progenitors (CMP, brown) in different stages of development and ICLC (blue). CMP have features of immature cardiomyocytes: a high nucleo-cytoplasmatic ratio and a continuous basal lamina (small arrows), numerous mitochondria (m) and ribosomes, few endoplasmic reticulum cisternae, some lipid droplets (l) and caveolae (*). These cells contain unorganized bundles of filaments (#) attached to electron dense structures (double arrows) similar to Z bands. (A) – ICLC processes (ICLCp) closely accompany the immature cardiomyocyte. B– The basal lamina exceeds the cellular profile and delimitates a slender acellular space. An ICLC process seems to support and direct this lamina (red dotted arrow). The large arrow indicates a gap junction in between two ICLCp. (C) – Note the presence of the subplasmalemmal leptofibrils (large arrows) and intracellular desmosome-like structures (arrowheads).