Skip to main content
. 2009 Sep 22;3(9):e519. doi: 10.1371/journal.pntd.0000519

Table 3. Antibiotic susceptibilities of B. pseudomallei strains.

Strain Known Genotype MIC (µg/ml) for:
Gma Str Spc Ery Cla Cli
1026b Wild-type 256 1024 512 128 64 >1024
DD503 1026b with Δ(amrR-amrAB-oprA) 2 NDb 64 8 4 >1024
708a 1 8 32 16 16 >1024
2188a 1 8 32 16 32 >1024
3799a 2 8 64 16 16 >1024
Bp24 Gmr derivative of 3799a >1024 1024 256 64 16 >1024
Bp35 Gmr derivative of 2188a >1024 >1024 >1024 256 512 >1024
Bp66 Low level Gmr derivative of 708a 32 8 16 4 16 >1024
Bp187 Bp24 with Δ(amrR-amrAB-oprA) 2 16 128 16 16 >1024
Bp202 Bp187::mini-Tn7T-LACc 4 32 128 8 16 >1024
Bp194 Bp187::mini-Tn7T-LAC-amrA + B +-oprA +c >1024 >1024 >1024 256 512 >1024
Bp192 Bp35 with Δ(amrR-amrAB-oprA) 2 16 128 16 16 >1024
Bp201 Bp192::mini-Tn7T-LACc 4 32 128 8 16 >1024
Bp200 Bp192::mini-Tn7T-LAC-amrA + B +-oprA +c >1024 >1024 >1024 256 256 >1024
a

Cla, clarithromycin; Cli, clindamycin; Ery, erythromycin; Gm, gentamicin; Spc, spectinomycin; Str, streptomycin.

b

ND, not done; DD503 is streptomycin resistant because of a chromosomal rpsL mutation.

c

The mini-Tn7 elements are integrated at the glmS2-associated Tn7 attachment site [20]. MIC values were determined in cells grown in the presence of 1 mM isopropyl-β-D-thiogalactopyranoside.