Table 3.
Genes that changed expression significantly (P < 0.05) upon 15-methoxypinusolidic acid treatment were functionally grouped (see Table 1)
| Gene ID | Gene symbol | Gene title | Fold change | P-value |
|---|---|---|---|---|
| 496423 | gadd45α | Growth arrest and DNA damage-inducible 45 α | 14.62 | 2.39E-03 |
| 807657 | cdkn2b | Cyclin-dependent kinase inhibitor 2B (p15, inhibits cyclin-dependent kinase 4) | 6.77 | 2.88E-07 |
| 930147 | gadd45γ | Growth arrest and DNA damage-inducible 45 γ | 2.07 | 3.42E-02 |
| 911031 | mcm4 | Minichromosome maintenance deficient 4 homologue | 0.49 | 5.96E-03 |
| 580590 | orc1l | Origin–recognition complex, subunit 1-like | 0.44 | 1.52E-02 |
| 466841 | ccne1 | Cyclin E1 | 0.37 | 3.10E-03 |
| 352483 | ccnd3 | Cyclin D3 | 0.35 | 3.40E-02 |
| 930704 | cdkn1c | Cyclin-dependent kinase inhibitor 1C (P57) | 0.34 | 4.41E-03 |
| 684806 | ccnd1 | Cyclin D1 | 0.31 | 9.48E-03 |
| 579729 | cdc6 | Cell division cycle 6 homologue | 0.24 | 3.47E-03 |
These are the genes from the cell cycle pathway.