Skip to main content
. Author manuscript; available in PMC: 2009 Sep 4.
Published in final edited form as: Annu Rev Nutr. 2008;28:347–366. doi: 10.1146/annurev.nutr.28.061807.155354

Figure 4.

Figure 4

Overview of the methionine-homocysteine-folate-B12 cycle, which provides methyl donors for methyltransferases. Nutritional regulations of the cycle by phytochemicals and metals are shown in red. BHMT, betaine homocysteine; CS, cystathionine synthase; DNMT, DNA methyltransferase; EGCG, epigallocatechin-3-gallate; MAT, methionine adenosyl transferase; MS, methionine synthase; SAAH, S-adenosyl-L-homocysteine hydrolase; SAH, S-adenosyl-L-homocysteine; SAM, S-adenosyl-L-methionine; THF, tetrahydrofolate.