Photomicrographs showing representative examples of ChAT-positive (ChAT+, arrows), pCREB-positive (pCREB+, small arrow head), and ChAT+ and pCREB+ (ChAT+/pCREB+, large arrow head) cells in the pedunculopontine tegmental nucleus (PPT, A-C) and laterodorsal tegmental nucleus (LDT, D-F) in animal sacrificed after control/baseline REM sleep (CR, A and D), low REM sleep (LR, B and E), and high REM sleep (HR, C and F) conditions. Scale bar in A for A-F = 100 μm.