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Efficacies of D21-6076 in mice models. Slc:ddY mice (10 animals per group) were rendered neutropenic by intravenous administration of cyclophosphamide. They were infected intravenously with C. albicans ATCC 90028 (2.6 × 104 cells) (A) or C. glabrata ATCC 48435 (2.4 × 108 cells) (B). D21-6076 was administered orally 1, 4, and 7 h after infection.
