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Correlation among the activities for β-1,6-glucan synthesis, adherence, and hyphal elongation of C. albicans. (A) The correlation among the IC50s of eight derivatives of D21-6076 for β-1,6-glucan synthesis and adherence is presented. Correlation coefficient (R2), 0.87. (B) The correlation among the IC50s of eight derivatives of D21-6076 for β-1,6-glucan synthesis and hyphal elongation is presented. Correlation coefficient, 0.65.
