FIG. 3.
Effects of MIV-210 on the serum WHV loads of woodchucks with chronic WHV hepatitis treated with an oral dose of 20 mg/kg/day (A) or 60 mg/kg/day (B) or with placebo during the 10-week treatment period and the 10-week follow-up period. Changes in WHV DNA loads in individual animals (upper panels) and mean changes in WHV viremia (lower panels) in sequential serum samples obtained from each of the three study groups were determined by quantifying WHV DNA using a dot blot hybridization test and, when that test was nonreactive, a PCR-NAH assay. The results are expressed in log10 virus genome equivalents per milliliter.