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Effect of hypoxia treatment on the growth of the M. tuberculosis sigB mutant strain. M. tuberculosis rolling broth cultures were grown at 37°C in sealed tubes. The figure shows the arithmetic means ± standard deviations for three biological replicates represented as ODs (A) or numbers of CFU/ml (B) of the cultures. Diamonds, H37Rv; squares, sigB mutant strain; triangles, complemented strain.
