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. 2000 May 20;320(7246):1373–1378. doi: 10.1136/bmj.320.7246.1373

Table 3.

Mean costs and effects for intensive and conventional blood glucose control policies

Item Intensive (n=2729) Conventional (n=1138) Mean difference (95%CI)
Mean (SD) cost/ patient (1997 £)
 Routine treatment:
 Antidiabetic treatment 1250 (1475) 591 (974) 659 (580 to 739)
  Blood glucose and HbA1c tests 420 (384) 281 (246) 139 (119 to 160)
 Antihypertensive drugs 525 (828) 523 (839) 2 (−56 to 60)
 Other drugs 71 (86) 69 (84) 2 (−4 to 8)
 Clinic visits 2504 (902) 2472 (915) 32 (−31 to 95)
 Total 4350 (2295) 3655 (1917) 695 (555 to 836)
Treatment of complications:
 Hospital inpatient 3494 (6827) 4266 (9580)  −772 (−1385 to −159)
 Non-hospital and outpatient 1631 (864) 1666 (899) −35 (−96 to 27)
 Eye and renal disease  133 (2222)  283 (5346) −150 (−472 to 171)
 Total 5258 (7593)  6215 (11450)  −957 (−1681 to −233)
Total trial 9608 (8343)  9869 (12022) −261 (−1027 to 505)
Total trial−6% discount 6958 (5774) 7170 (8689) −212 (−761 to 338)
Total non-trial setting 8349 (8153)  7871 (11841)  478 (−275 to 1232)
Total non-trial setting−6% discount 6027 (5674) 5689 (8615) 338 (−207 to 882)
Mean (SD) event-free years/patient
 Within trial event-free years 14.89 (6.93) 14.29 (7.06) 0.60 (0.12 to 1.10)
Discounted at 6% 9.17 (3.20) 8.88 (3.44) 0.29 (0.06 to 0.53)
Unbiased estimate of event-free years 15.08 (7.20) 13.94 (6.89) 1.14 (0.69 to 1.61) 

HbA1c=glycated haemoglobin.