Table 3.
Item | Intensive (n=2729) | Conventional (n=1138) | Mean difference (95%CI) |
---|---|---|---|
Mean (SD) cost/ patient (1997 £) | |||
Routine treatment: | |||
Antidiabetic treatment | 1250 (1475) | 591 (974) | 659 (580 to 739) |
Blood glucose and HbA1c tests | 420 (384) | 281 (246) | 139 (119 to 160) |
Antihypertensive drugs | 525 (828) | 523 (839) | 2 (−56 to 60) |
Other drugs | 71 (86) | 69 (84) | 2 (−4 to 8) |
Clinic visits | 2504 (902) | 2472 (915) | 32 (−31 to 95) |
Total | 4350 (2295) | 3655 (1917) | 695 (555 to 836) |
Treatment of complications: | |||
Hospital inpatient | 3494 (6827) | 4266 (9580) | −772 (−1385 to −159) |
Non-hospital and outpatient | 1631 (864) | 1666 (899) | −35 (−96 to 27) |
Eye and renal disease | 133 (2222) | 283 (5346) | −150 (−472 to 171) |
Total | 5258 (7593) | 6215 (11450) | −957 (−1681 to −233) |
Total trial | 9608 (8343) | 9869 (12022) | −261 (−1027 to 505) |
Total trial−6% discount | 6958 (5774) | 7170 (8689) | −212 (−761 to 338) |
Total non-trial setting | 8349 (8153) | 7871 (11841) | 478 (−275 to 1232) |
Total non-trial setting−6% discount | 6027 (5674) | 5689 (8615) | 338 (−207 to 882) |
Mean (SD) event-free years/patient | |||
Within trial event-free years | 14.89 (6.93) | 14.29 (7.06) | 0.60 (0.12 to 1.10) |
Discounted at 6% | 9.17 (3.20) | 8.88 (3.44) | 0.29 (0.06 to 0.53) |
Unbiased estimate of event-free years | 15.08 (7.20) | 13.94 (6.89) | 1.14 (0.69 to 1.61) |
HbA1c=glycated haemoglobin.