FIG. 5.

Infection dynamics of V. cholerae N16961 and a sialic acid catabolism-deficient strain in the suckling mouse intestine. Three- to 5-day-old CD-1 mice were inoculated with V. cholerae N16961 or V. cholerae SAM1776 (ΔnanA). Six mice were used per strain and time point. The intestines were removed after 1, 3, 6, 9, 12, and 24 h. Serial dilutions of the homogenates were plated on LB containing Sm and the CFU counted. We used the paired t test to compare the numbers of CFU of N16961 and SΑΜ1776 at the same time point. ***, P < 0.0005. Error bars indicate standard deviations.