TABLE 2.

Species compositions of vaginal communities in women with and without frequent VVC

Phylotypea	% of phylotypes in communities
	Cluster Ib				Cluster II				Cluster III (Y36; n = 96)c	Cluster IV (Y23; n = 96)c
	Y12 (n = 96)c	Y41 (n = 95)	Y35 (n = 93)	Y2 (n = 96)	Y14 (n = 95)c	Y19 (n = 96)c	Y30 (n = 94)	Y37 (n = 96)c
L. crispatus	86.5	89.5	94.6	99	24.2	0	0	16.7	0	0
L. iners	0	7.4	2.2	0	56.8	76	81.9	43.8	0	29.2
L. gasseri	13.5	0	0	0	0	4.2	0	0	100	0
L. jensenii	0	1.1	1.1	0	12.6	15.6	16	30.2	0	9.4
L. galinarum	0	0	0	0	1.1	0	0	0	0	0
L. kitasatonis	0	0	1.1	0	1.1	0	0	0	0	0
L. vaginalis	0	0	1.1	0	0	0	0	0	0	0
Lactobacillus sp. strain KC38d	0	2.1	0	1	4.2	4.2	1.1	9.4	0	5.2
A. vaginae	0	0	0	0	0	0	0	0	0	55.2
Diaphorobacter sp.	0	0	0	0	0	0	1.1	0	0	0
Prevotella bivia	0	0	0	0	0	0	0	0	0	1

^aClones were classified by comparing their 16S rRNA gene sequences to those of known organisms. Genus and species names were used if the sequence similarity to a type species was >97%; only the genus only was used if the sequence similarity was <97% but >90%.

^bCommunity clusters are based on T-RFLP analysis of 16S rRNA genes. See Fig. 1. The numbers of women with the clusters were as follows: cluster I, 24; cluster II, 10; cluster III, 4; and cluster IV, 3.

^cWoman with frequent VVC. n is the number of clones in the library that were sequenced.

^dLactobacillus sp. strain KC38 was first characterized by Pavlova et al. (26), and it is phylogenetically distinct from known species of Lactobacillus.