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The absence of flagellin increases ICAM-1 expression on macrophages and DCs in a systemic model. PP cells of wild-type and TLR5−/− mice noninfected (NI) or infected with WT S. enterica serovar Typhimurium or an aflagellate mutant (C−B−) were isolated at day 4 postinfection, gated on F4/80 or CD11c, and stained for ICAM-1 for flow cytometric analysis. Data are representative of at least six individually analyzed mice.
