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C3 deficiency increases susceptibility to infection with C. glabrata. C57BL/6 wild-type (•) and C3-deficient (○) mice were infected with 7 × 107 CFU of C. glabrata i.v. and were monitored for survival over 21 days, as described in Materials and Methods. The data shown are pooled from two independent experiments. *, P < 0.05.
