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C3 and C5 deficiency protects against lethality induced upon high-dose infection with S. cerevisiae. C57BL/6 wild-type or C3-deficient, DBA/2, and BALB/c mice were infected with 1 × 108 CFU of S. cerevisiae i.v. and were monitored for survival over 21 days, as described in Materials and Methods. The data shown are pooled from two independent experiments. *, P < 0.05.
