FIG. 4.

Pulmonary inflammation. Whole lungs were harvested at day 5, day 7, and day 9 after MHV-1 infection for each of the indicated mouse strains. The lungs were fixed in 10% neutral buffered formalin, embedded in paraffin, and sectioned prior to being stained with hematoxylin and eosin. The slides were scored for total inflammation (A) and total edema (B) according to the scales described in Materials and Methods. The results from two combined experiments are expressed as the mean of a total five to eight mice per group. The error bars indicate the standard deviations. *, P < 0.05 as determined by ANOVA for the comparisons indicated.