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. 2009 Jul 1;83(17):8315–8326. doi: 10.1128/JVI.00633-09

FIG. 5.

FIG. 5.

Spread to the brain. Mice were infected in the vitreous body with WT, mutant, or rescue strain HSV-1, and tissues were harvested 5 dpi. (A) Anterograde transport to the optic tract (black arrows) and multisynaptic retrograde spread to the suprachiasmatic nucleus (white arrows). (B) Anterograde transport to the optic tract (black arrows) and anterograde spread to the lateral geniculate nucleus (black arrowheads). (C) Anterograde spread to the superior colliculus (black arrows) and retrograde spread to the oculomotor and Edinger-Westphal nuclei (white arrows). Magnification, ×20.