FIG. 9.

DC infiltration into the ILN of HSV-2-infected mice is reduced in the absence of CXCR3. WT and CXCR3^−/− mice (six mice/group) were infected with HSV-2 (2,000 PFU/vagina) and subsequently exsanguinated at the indicated time points p.i. ILN samples were processed and analyzed for B220⁻ CD11c⁺ DCs (A), plasmacytoid DCs (CD11c⁺ B220⁺) (B), and total CD11c⁺ DCs expressing CD80 (C) by flow cytometry on day 3 p.i. The data are displayed as the means ± standard errors of the means from three independent experiments. *, P was <0.05 when comparing WT and CXCR3^−/− mice.