TABLE 1.
Group and animal | Result for animala |
Viremia on day 10 p.i. (SIV RNA copy equivalents/ml) | Necropsy (days p.i.) | |
---|---|---|---|---|
Inoculated with SIV | Treated with HAART | |||
SIV infected, HAART treated | ||||
PEz1 | + | + | 3.5 × 108 | 165 |
PFy1 | + | + | 1.4 × 108 | 172 |
PTa2 | + | +* | 9.8 × 107 | 161 |
PYd2 | + | +* | 1.5 × 108 | 168 |
POy1 | + | +** | 1.4 × 108 | 175 |
SIV infected, untreated | ||||
PDi2 | + | − | 1.1 × 108 | 83 |
PSk2 | + | − | 9.9 × 107 | 87 |
PUi2 | + | − | 8.8 × 108 | 88 |
PEi2 | + | − | 2.0 × 108 | 84 |
Uninfected animals | ||||
PBk2 | − | − | − | 89 |
PNk2 | − | − | − | 90 |
*, doses of PMPA were reduced to 10 mg/kg at day 71 p.i. until necropsy; **, doses of PMPA were reduced to 10 mg/kg at day 71 p.i. PMPA was removed from the HAART regimen at day 107.