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. 2009 Jul 1;83(18):9521–9531. doi: 10.1128/JVI.00583-09

FIG. 4.

FIG. 4.

Regulation of E2F target genes by TAg and mutants. Mice expressing TAgwt and TAgN136 show significant upregulation of E2F target genes, while mice expressing TAg3213 and TAgD44N do not. The average fold change of the genes was determined by microarray analysis of each category (n = 3): TAgwt, TAgN136, TAg3213, and TAgD44N. “Normalization” represents a fold change of 1 (not regulated).