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. 2008 Jul-Sep;50(3):202–208. doi: 10.4103/0019-5545.43634

Table 1.

Important functions and corresponding impairments associated with prefrontal cortex

Function Impairment
Attention Impaired attention to novel stimuli, impaired selective attention
Memory and learning Poor working memory (impairment in brief and transient storage and processing of information)
Poor temporal memory (difficulty in remembering temporal status of events i.e., difficulty in ascertaining relative recency of different events)
Poor prospective memory (difficulty in remembering intentions for carrying out future actions)
Increased sensitivity to proactive interference
Executive functions Poor planning of behavior
Poor strategy formation and problem solving
Poor decision making
Poor set-shifting
Motor behavior Unsystematic gaze movements
Poor movement programming (e.g., problem in alternating movements of hands)
Poor fine movement
Motor impersistence, perseveration
Unilateral hypokinesia and unilateral motor neglect
Speech Expressive aphasia
Decreased verbal fluency
Self-control Grasp reflex (automatic tendency to grip objects coming in contact of hand)
Groping response (the hand tends to follow and manipulate an object, e.g., holding, rubbing, etc., following tactile stimulation. Apart from hands, often the eyes also follow the object in somewhat magnetic fashion)
Imitation behavior (tendency to imitate other's gestures or movements)
Utilization behavior (appropriate movement done in a context that is inappropriate, e.g., while eating the patient may pick up a comb and start combing his hair just because a comb has been kept in front of him by someone)
Abstract thinking More reliance on concrete and superficial clues
Affect Inappropriate or blunted affect
Sphincter control Little or no concern about urinating or defecating at inappropriate places