Table 3.
DDD versus IC-MPGN LCMS findings
| Pathology Protein |
DDD (n=8) |
IC-MPGN (n=9) |
||
|---|---|---|---|---|
| >95%a | >80% | 95% | >80% | |
| C3 | 8 | 8 | 6 | 7 |
| C4 | 3 | 3 | 5 | 8 |
| C5 | 7 | 7 | 1 | 1 |
| C6 | 4 | 6 | 1 | 1 |
| C7 | 1 | 4 | 0 | 0 |
| C8α | 3 | 5 | 0 | 0 |
| C8β | 2 | 7 | 0 | 0 |
| C8γ | 2 | 5 | 0 | 0 |
| C9 | 8 | 8 | 3 | 5 |
| Immunoglobulin | 0 | 0 | 9 | 9 |
| FHR1 | 8 | 8 | 6 | 7 |
| FHR5 | 1 | 2 | 0 | 0 |
| Clusterin | 8 | 8 | 4 | 6 |
| Vitronectin | 8 | 8 | 1 | 3 |
| Apolipoprotein E | 8 | 8 | 0 | 0 |
DDD, dense deposit disease; IC-MPGN, immune complex-mediated membranopro-liferative glomerulonephritis; LCMS, liquid chromatography and mass spectrometry; FHR, factor H-related protein.
a
Protein prediction probability.