Table 3.
Childhood Cancer Survivor Study Radiotherapy: Anatomic Regions With One or More Radiation Fields
| First Malignant Neoplasm | Sites Treated |
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain |
Head (not brain) |
Cranio-Spinal* |
Neck |
Chest |
Spine |
Abdomen |
Pelvis |
Limb |
Total-Body Irradiation |
Region Unknown |
||||||||||||
| No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | |
| Leukemia (n = 2,927) | 2,666 | 91.1 | 77 | 2.6 | 442 | 15.1 | 69 | 2.4 | 93 | 3.2 | 443 | 15.1 | 77 | 2.6 | 379 | 12.9 | 26 | 0.9 | 244 | 8.3 | 56 | 1.9 |
| CNS (n = 1,166) | 1,096 | 94.0 | 70 | 6.0 | 416 | 35.7 | 63 | 5.4 | 26 | 2.2 | 428 | 36.7 | 24 | 2.1 | 26 | 2.2 | 3 | 0.3 | 1 | 0.1 | 32 | 2.7 |
| Hodgkin's lymphoma (n = 1,584) | 15 | 0.9 | 190 | 12.0 | 1 | 0.1 | 1,484 | 93.7 | 1,435 | 90.6 | 1 | 0.1 | 989 | 62.4 | 609 | 38.4 | 34 | 2.1 | 4 | 0.3 | 30 | 1.9 |
| Non-Hodgkin's lymphoma (n = 639) | 178 | 27.9 | 150 | 23.5 | 39 | 6.1 | 239 | 37.4 | 264 | 41.3 | 41 | 6.4 | 152 | 23.8 | 160 | 25.0 | 48 | 7.5 | 17 | 2.7 | 13 | 2.0 |
| Kidney tumor (n = 694) | 4 | 0.6 | 1 | 0.1 | 16 | 2.3 | 263 | 37.9 | 673 | 97.0 | 342 | 49.3 | 3 | 0.4 | 9 | 1.3 | ||||||
| Neuroblastoma (n = 414) | 41 | 9.9 | 35 | 8.5 | 11 | 2.7 | 72 | 17.4 | 171 | 41.3 | 15 | 3.6 | 215 | 51.9 | 115 | 27.8 | 10 | 2.4 | 16 | 3.9 | 8 | 1.9 |
| Soft-tissue tumor (n = 694) | 64 | 9.2 | 272 | 39.2 | 6 | 0.9 | 120 | 17.3 | 124 | 17.9 | 7 | 1.0 | 84 | 12.1 | 191 | 27.5 | 131 | 18.9 | 1 | 0.1 | 15 | 2.2 |
| Bone tumor (n = 388) | 30 | 7.7 | 20 | 5.2 | 5 | 1.3 | 24 | 6.2 | 168 | 43.3 | 5 | 1.3 | 47 | 12.1 | 95 | 24.5 | 185 | 47.7 | 3 | 0.8 | 9 | 2.3 |
| Total (N = 8,506) | 4,094 | 48.1 | 815 | 9.6 | 920 | 10.8 | 2,087 | 24.5 | 2,544 | 29.9 | 940 | 11.1 | 2,261 | 26.6 | 1,917 | 22.5 | 440 | 5.2 | 286 | 3.4 | 172 | 2.0 |
NOTE. Includes radiotherapy at any time. Rows sum to more than 100% due to some patients receiving treatment to multiple regions.
*
Cranio-spinal added as a category for patients who were treated to the brain and spine. Brain and spine may not have been treated at the same time or to the same dose. Patients with cranio-spinal treatments also are counted in both the ″brain″ and ″spine″ categories.