CD4+ T cells, but not asialo-GM1+ cells, are essential for IL-13 driven immunity in female IL-4KO BALB/c mice. IL-4KO BALB/c mice females were injected with Control Rabbit Ig, anti-asialo GM1 or anti CD4 antibodies to neutralise NK and CD4+ T cells, respectively. A) Worm burdens of susceptible male IL-4KO control mice and female IL-4KO mice were assessed after treatment at day 28 p.i. (n=5) B) Levels of pro-inflammatory cytokines in E/S restimulated MLNC cultures were measured via CBA assay (IL-6 and TNF-α) and ELISA (IL-17) from culture restimulations of MLNCs, * - p≤0.05, ** - p ≤0.01, *** - p≤0.001.