Table 2.
Subgroup | Hazard ratio (95%CI) | p value | 5-year survival rate (95%CI) (%) | p value (log-rank) |
All patients (n = 179) | ||||
'CK5/6 or 14 or 17' | 1.46 (0.90–2.37) | 0.127 | 0.124 | |
Positive | 63.5 (50.7–73.8) | |||
Negative | 75.3 (66.1–82.4) | |||
Vimentin | 1.22 (0.69–2.14) | 0.497 | 0.496 | |
Positive | 59.5 (42.1–73.3) | |||
Negative | 73.9 (65.7–80.4) | |||
'Vimentin or CK5/6 or | 1.73 (1.07–2.81) | 0.026 | 0.024 | |
14 or 17' | ||||
Positive | 61.5 (49.3–71.6) | |||
Negative | 77.6 (68.2–84.5) | |||
Triple negative patients (n = 54) | ||||
'CK5/6 or 14 or 17' | 0.50 (0.21–1.20) | 0.122 | 0.115 | |
Positive | 71.8 (54.9–83.3) | |||
Negative | 52.5 (25.2–74.0) | |||
Vimentin | 0.64 (0.28–1.48) | 0.297 | 0.293 | |
Positive | 69.0 (48.8–82.5) | |||
Negative | 68.0 (46.1–82.5) | |||
'Vimentin or CK5/6 or | 0.56 (0.22–1.45) | 0.234 | 0.227 | |
14 or 17' | ||||
Positive | 78.6 (62.9–88.2) | |||
Negative | 58.3 (27.0–80.1) | |||
Non-triple negative patients (n = 125) | ||||
'CK5/6 or 14 or 17' | 2.61 (1.40–4.84) | 0.002 | 0.002 | |
Positive | 50.9 (30.7–67.9) | |||
Negative | 77.8 (67.9–84.9) | |||
Vimentin* | 3.26 (1.37–7.77) | 0.008 | 0.005 | |
Positive | 25.4 (3.8–56.4) | |||
Negative | 75.2 (66.1–82.2) | |||
'Vimentin or CK5/6 or | 3.04 (1.66–5.56) | <0.001 | <0.001 | |
14 or 17' | ||||
Positive | 47.5 (29.1–63.8) | |||
Negative | 80.1 (70.2–87.0) |
*In a non-triple negative group only 9 patients were positive for vimentin. Thus, results of survival analysis should be regarded as being inconclusive and they are showed for comparative purposes only.