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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Childs Nerv Syst. 2009 Feb 11;25(10):1275–1282. doi: 10.1007/s00381-009-0809-7

Table 1.

Results of Prospective Clinical Trials for Infants and Young Children with Ependymoma

Event Free Survival Overall Survival References

Trial N Age (mo) 1 year 5 years (unless otherwise specified) 5 years (unless otherwise specified)


CCG 8-in-1 15 22 (3) 8

HIT 88/89/91 55 75.6 (3) 24
GTR 28
STR 27

Baby POG 8633 48 <36 25 40.5 25
GTR 23 66
8 0–24 87 25.7 37.5
8 24–36 94 63.3 87.5
STR 25 25

SFOP 73 22 (4) 59 (4) 26
GTR 74 (4)
STR 35 (4)

VETOPEC 14 36 (3) 27

CCG 9921 74 72 32 59 12
M0 with min residual 42 79 33 67
20 75 29 54
M0, other 12 42 33 40
M1+

MD Anderson 5 40 (>5) 28

Head Start I/II 29 12 38 29
GTR 18 42
STR 11 31