Table 6.
Haplotype analysis of two-SNP TNF-α haplotype in IBD status in New Zealand IBD patients and Caucasians
| Haplotype | Case subject frequency (%) | Control subject frequency (%) | Hap-score | Haplotype-specific scores P | Global score statistics | |
| CD | Two SNPs TNF-α region | |||||
| [-308 (rs1800629), -238 (rs361525)] | ||||||
| GG | 75.3 | 76.7 | -0.76 | 0.45 | χ2 = 0.85, df = 3, P = 0.82 | |
| GA | 6.2 | 6.0 | 0.32 | 0.75 | ||
| AG | 18.2 | 17.3 | 0.59 | 0.56 | ||
| UC | Two SNPs TNF-a region | |||||
| [-308 (rs1800629), -238 (rs361525)] | ||||||
| GG | 73.9 | 76.4 | -1.31 | 0.19 | χ2 = 3.37, df = 2, P = 0.18 | |
| GA | 5.3 | 6.0 | -0.63 | 0.53 | ||
| AG | 20.8 | 17.5 | 1.79 | 0.07 |