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A: Effect of amiRNA-HBV with stable transfection on HBsAg levels; B: Effect of amiRNA-HBV with stable transfection on HBeAg levels. HBsAg and HBeAg levels are expressed as mean ± SD. Compared with negative control, all three plasmids had significant inhibitory effect on HBsAg and HBeAg (HBsAg: P = 0.00019, 0.000035 and 0.000012, respectively; HBeAg: P = 0.003, 0.0002 and 0.000024, respectively).
