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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: J Pharm Sci. 2009 Aug;98(8):2677–2685. doi: 10.1002/jps.21642

Table 2.

Mean pharmacokinetic parameters of cephalexin determined by ETS, microdialysis techniques following administration of 20mg/kg by i.v bolus in hairless rats (n=6 ± sd).

Parameter ETS Microdialysis P- value
Tmax (min) 120 120 --
Cmax (µg/ml) 13.09 ± 1.92 12.64 ± 1.90 0.39
AUC0–6(min*µg/ml) 2512.35 ± 250.14 2473.66 ± 202.43 0.42
t1/2 (min) 106.61 ± 17.81 96.37 ± 12.33 0.22