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. Author manuscript; available in PMC: 2009 Sep 6.
Published in final edited form as: J Mol Biol. 2007 Dec 4;376(3):736–748. doi: 10.1016/j.jmb.2007.11.075

Table 2. Thermal stability, mean residual ellipticity at 225 nm and calorimetric enthalpy values for peptides containing a G1G interruption and homologous control peptides, in PBS (pH 7).

Peptide Peptide Sequence Tm MRE225nm ΔHcal
Name (°C) (deg cm2 dmol-1) (kJ/mol)
GF a (GPO)3GPOG*F*GPO(GPO)2G*POGPOGYb 21 2950 100
GFO a (GPO)3GPOGFOGPO(GPO)4GY 44 5500 221
GY Ac-(GPO)3GPOGYGPQ(GPO)4G-NH2 26.5 3966 310
GYO Ac-(GPO)3GPOGYOGPQ(GPO)4G-NH2 48.5 5120 357
GP (POG)3POGPGPO(GPO)4G <5 (15c) n.a n.a
GPO (POG)10 58 4012 390
GV Ac-(GPO)3GPOGAAGVGPO(GPO)3GY-NH2 27.5 3006 187
GAAVM d Ac-(GPO)3GPOGAAVMGPO(GPO)3GY-NH2 29.1 2360 188
GAAGVM Ac-(GPO)3GPOGAAGVMGPO(GPO)3GY-NH2 39.7 4950 354
a

= dissolved in glycine buffer with 0.6M GuHCl, pH 2.0.

b

= * indicates 15N labeled residues

c

= Reported previously in 0.1M acetic acid 20

d

= Reported previously 18