Table 1.

Laboratory data and parasite multiplication rates for patients included in the PMR study in Kenya and Mali^*

	No.	Age (months)	Hb (g/dL)	Parasitemia† (%)	WBCs (× 109/L)	Rosette frequency‡	Parasite multiplication rate
Kenya
All patients	33	33 (30) [30]	8.7 (2.6) [27]	6.0 (4.1)	13.7 (12.0) [27]	1.3 (0–5.5) [20]	2.2 (1.1–3.3)
Uncomplicated	20	44 (35) [17]	9.8 (1.3) [14]	4.0 (2.3)	9.0 (3.6) [14]	1.0 (0–3) [12]	2.3 (1.2–3.6)
Severe§	13	20 (11)	7.5 (3.1)	9.1 (4.5)	18.8 (15.6)	3.3 (0–19.3) [8]	1.8 (1.0–2.9)
P		0.02	0.0125	0.0001	0.003	0.32	0.38
Mali
All patients	61	39 (22)	9.6 (1.8)	8.2 (7.8)	14.0 (7.2) [60]	7.0 (0–17)	2.6 (1.8–3.5)
Uncomplicated	23	40 (22)	9.6 (1.5)	3.0 (1.7)	13.2 (7.4) [22]	2.0 (0–12)	3.1 (2.3–4.4)
Severe	19	34 (22)	8.7 (2.4)	7.3 (4.3)	15.7 (8.3)	14.0 (9–24)	2.8 (2.1–3.5)
Hyperparasitemic	19	42 (24)	10.4 (1.1)	15.4 (9.4)	13.1 (5.9)	5.0 (2–20)	1.8 (1.2–2.7)
P		0.54	0.04	< 0.0001	0.48	0.003	0.27¶ 0.03#

^*Values are the mean (SD) or median (interquartile range). Values in square brackets indicate no. of patients that differ due to missing data. Hb = hemoglobin; WBC = white blood cells. Rosette frequency and parasite multiplication rates were analyzed by the Mann-Whitney U test (Kenya) or the Kruskal-Wallis test (Mali). Other parameters were analyzed by analysis of variance or Student’s t-test.

^†Percentage of infected red blood cells in 1,000 red blood cells counted.

^‡Percentage of infected red blood cells binding ≥ 2 uninfected red blood cells in 200 infected red blood cells counted.

^§Mean (SD) values for additional biochemical tests in severe case are pH 7.34 (0.15), bicarbonate 16.04 mmol/L (5.90), and lactate 5.03 mg/dL (3.56). These tests were not available for uncomplicated cases in Kenya or any samples from Mali.

^¶Severe versus uncomplicated by Mann-Whitney U test.

^#Severe, uncomplicated, and hyperparasitemia groups by Kruskal-Wallis test.