Table 1.
Baseline characteristics of patients and caregivers
| Mann-Whitney | country | Kruskal-Wallis (df=2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total (N=155) |
Treatment (n=79) | controls (n=76) | Z | p | AUS (n=52) | UK (n=51) | USA (n=52) | chi2 | p | ||
| Patients | age: M(SD) | 73.8 (7.48) | 73.9 (7.74) | 73.7 (7.28) | −0.858 | 0.391 | 75.0 (7.23) | 72.9 (6.37) | 73.0 (8.55) | 2.463 | 0.292 |
| gender: M:F | 87:68 | 47:32 | 40:36 | 31:21 | 22:29 | 34:18 | |||||
| MMSE: M(SD) | 20.3 (5.61) | 20.9 (5.16) | 19.8 (5.99) | −0.581 | 0.561 | 20.0 (5.46) | 20.3 (6.22) | 20.7 (5.27) | 0.453 | 0.797 | |
| ADCS-ADL: M(SD) | 55.3 (13.32) | 56.7 (11.41) | 54.0 (14.85) | −0.045 | 0.964 | 54.4 (12.91) | 53.5 (14.0) | 58.1 (13.03) | 6.559 | 0.038 | |
| ADAS-Cog: M(SD) | 25.8 (11.40) | 25.7 (11.11) | 25.9 (11.73) | −0.206 | 0.837 | 28.8 (10.45) | 21.1 (12.29) | 26.8 (10.79) | 12.876 | 0.002 | |
| GDS: M(SD) | 4.4 (0.53) | 4.4 (0.49) | 4.4 (0.58) | −0.406 | 0.685 | 4.4 (0.50) | 4.2 (0.54) | 4.5 (0.55) | 3.207 | 0.201 | |
| RMBPCL: M (SD) | 9.84 (8.43) | 10.04 (8.91) | 9.63 (7.96) | −.062 | 0.951 | 9.23 (9.27) | 9.31 (8.05) | 10.98 (7.94) | 3.437 | 0.179 | |
| Phys. health | 5.7 (1.51) | 5.5 (1.52) | 5.8 (1.50) | −1.61 | 0.107 | 5.5 (1.38) | 5.8 (1.70) | 5.8 (1.54) | 0.314 | 0.855 | |
| Caregivers | age: M (SD) | 71.3 (8.2) | 71.5 (7.98) | 71.1 (8.41) | −0.641 | 0.521 | 71.8 (8.20) | 72.6 (5.63) | 69.6 (9.46) | 1.133 | 0.567 |
| gender M:F | 69:86 | 33:46: | 36:40: | 21:31 | 29:22 | 19:33 | |||||
| BDI: M(SD) | 8.7 (6.53) | 9.2 (7.02) | 8.3 (6.05) | −0.508 | 0.611 | 9.1 (5.48) | 7.1 (6.68) | 9.8 (7.30) | 3.001 | 0.223 | |
M: mean, SD: Standard deviation, USA: United States of America, UK: United Kingdom, AUS: Australia; Significant results are printed bold