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. Author manuscript; available in PMC: 2009 Sep 7.
Published in final edited form as: Trends Biochem Sci. 2007 Oct 22;32(11):500–508. doi: 10.1016/j.tibs.2007.08.007

Figure I.

Figure I

Structures of TCR and MHC class II molecules. The genes coding for TCR are split into several subgenes (V, D, J, C); V, D, and J exist in numerous copies. Somatic recombination of these subgenes during T-cell development generates vast numbers of rearranged TCR genes that encode the α and β chains of the receptor.