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. Author manuscript; available in PMC: 2010 Aug 19.

Published in final edited form as: J Am Chem Soc. 2009 Aug 19;131(32):11306–11307. doi: 10.1021/ja9048338

Table 1.

Thermodynamic parameters for ARNT PAS-B Y456T.

	Parameter	Value
Interconversion +3 → WT	ΔG^‡	18.0 kcal/mol
	ΔH^‡	12.7 kcal/mol
	ΔS^‡	−17.8 cal/mol·K (−5.3 kcal/mol @ 298 K)
Unfolding	ΔG^‡	21.6 kcal/mol
	ΔH^‡	11.8 kcal/mol
	ΔS^‡	−32.9 cal/mol·K (−9.8 kcal/mol @ 298 K)