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. Author manuscript; available in PMC: 2009 Nov 28.
Published in final edited form as: Cell. 2008 Nov 20;135(5):933–947. doi: 10.1016/j.cell.2008.10.011

Figure 3. Dynamic monitoring of ER redox status and UPR activity in ER oxidative folding, quality control, and UPR signaling mutants during pharmacologically-induced ER stress.

Figure 3

(A–L) Median eroGFP ratio (green circles) and UPR-RFP metric (red x-marks) during treatment with DTT (2mM) or Tm (1µg/ml) for wild-type and indicated mutants. Values are normalized to wild-type unstressed cells. Dashed gray line signifies time at which stressor was added.