Table 2.

Compared enrichment variations over 5 methods

	CDK2	FXa	NA	RNAse	TK
Enrichment 1%
CSR	11–56	0–63	33–100	100-100	22–78
SM	22–67	0–63	44–67	43–100	22–78
RC	11–56	0–38	67–100	29–57	44–100
2D	0–33	0–38	22–89	100-100	22–89
Enrichment 3%
CSR	33–56	0–63	56–100	100-100	33–89
SM	22–67	0–75	56–100	43–100	56–100
RC	22–67	0–63	78–100	29–86	56–100
2D	11–56	0–38	22–89	100-100	44–100

For 5 families of active compounds, we present for LigCSRre (CSR), MED-SuMoLig (SM), ROCS-cff (RC) and ChemMine (2D), the minimal and maximal enrichment scores at 1% and 3%. Results expressed in % of recovered co-active ligands.