Table 1.
Genes included on Taqman array, classified by their major contribution to drug resistance mechanisms.
| Apoptosis | DNA repair | Proliferation | Pumps/Detox |
|---|---|---|---|
| AKT | ATM | APC C-term | ATP7B |
| APAF1 | BRCA1 | APC N-term | BCRP |
| BAD | ERCC1 | β-TUBULIN III | CES1 |
| BAX | ERCC2 | COX2 | CES2 |
| BCL2 | GTF2H2 | EGFR | cN II |
| BCL-x(L) | MGMT | HER2 | DPD |
| BID | MLH1 | HER3 | FPGS |
| c-FLIP | MSH2 | HER4 | γ H2AX |
| FAS | MSH6 | HIF1A | GCLC |
| FASL | RAD51 | KI67 | GCLM |
| HSP60 | TOPO I | P16 | GSTπ |
| HSP70 | TOPO IIa | P21 | hENT1 |
| HSP90 | TOPO IIb | P27 | hENT2 |
| IAP2 | XPA | P53 | MDR1 |
| IGF1 | XRCC1 | VEGF | MRP1 |
| IGF1R | XRCC5 | MRP2 | |
| IGF2 | XRCC6 | MRP3 | |
| IGF2R | MRP4 | ||
| IGFBP1 | MRP5 | ||
| IGFBP2 | MRP6 | ||
| MCJ | MRP8 | ||
| MCL1 | MTII | ||
| mTOR | MVP | ||
| NFkB | House-keeping gene | OPRT | |
| PIK3CA | 18S | RRM1 | |
| PTEN | HPRT | SOD1 | |
| STAT3 | PBGD | TAP1 | |
| SURVIVIN | SDHA | TAP2 | |
| XIAP | TBP | TAP4 | |