Changes in renal and splenic SND (combined for presentation) during increases in Tc from 38° to 41.5°C and for 3 min following muscimol microinjections (Tc maintained at 41.5°C) in RVLM sites (RVLM mus, 400 pmol; open circles, n=11) and in sites identified to be functionally outside the RVLM (non-RVLM mus, 400 pmol; closed circles, n=5). *RVLM and non-RVLM microinjections significantly different from control (38°C). ** RVLM muscimol significantly different from non-RVLM muscimol at 1, 2 and 3 min post-microinjection.