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. 2009 Jul 15;29(28):9104–9114. doi: 10.1523/JNEUROSCI.2250-09.2009

Figure 3.

Figure 3.

Deletion of Hsp70.1/3 exacerbates the physical phenotypes of R6/2 mice. The absence of Hsp70.1/3 significantly exacerbates the weight loss phenotype (two-way ANOVA: p < 0.05) (A), and worsens the coat appearance (two-way ANOVA: p < 0.001) (B), body position (two-way ANOVA: p < 0.02) (C), and tail position (two-way ANOVA p < 0.001) (D) of R6/2 mice. Error bars indicate SEM. Note that in the absence of the R6/2 transgene, the loss of one or both copies of Hsp70.1/3 does not influence any of the presented outcome measures.