Table 1.
Year published | Country | Study type | Number of patients on steroids only at follow-up | Number of patients on steroids plus antivirals at follow-up | Type of steroid | Steroid dose | Type of antiviral | Antiviral dose | |
---|---|---|---|---|---|---|---|---|---|
Adour et al22 | 1996 | United States | RCT (double blind) | 46 | 53 | Prednisolone oral | 1 mg/kg/day for 5 days followed by taper to 10 mg/kg/day over 5 days | Aciclovir | 2000 mg/day for 10 days |
Hato et al12 | 2007 | Japan | RCT (single blind) | 107 | 114 | Prednisolone oral | 60 mg/day for 5 days, 30 mg/day for 3 days, 10 mg/day for 2 days | Valaciclovir | 1000 mg/day for 5 days |
Sullivan et al6 | 2007 | United Kingdom | RCT (double blind) | 127 | 124 | Prednisolone oral | 50 mg/day for 10 days | Aciclovir | 2000 mg/day for 10 days |
Engstrom et al14 | 2008 | Sweden | RCT (double blind) | 180 | 186 | Prednisolone oral | 60 mg/day for 5 days, 50 mg/day for 1 day, 40 mg/day for 1 day, 30 mg/day for 1 day, 20 mg/day for 1 day, 10 mg/day for 1 day | Valaciclovir | 3000 mg/day for 7 days |
Minnerop et al9 | 2008 | Germany | RCT (not blinded) | 67 | 50 | Prednisone oral | 1 mg/kg/day for 4 days, taper over 8 days | Famciclovir | 250 mg/day for 7 days |
Yeo et al10 | 2008 | South Korea | RCT (double blind) | 47 | 44 | Prednisolone oral | 1 mg/kg/day for 4 days, 60 mg/kg/day for 2 days, 40 mg/kg/day for 2 days, 20 mg/kg/day for 2 days | Aciclovir | 2400 mg/day for 5 days |
RCT, randomised controlled trial.