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. 2009 Sep 7;339:b3354. doi: 10.1136/bmj.b3354

Table 1.

Study demographics and therapeutic treatments prescribed in the six studies included in the meta-analysis

Year published Country Study type Number of patients on steroids only at follow-up Number of patients on steroids plus antivirals at follow-up Type of steroid Steroid dose Type of antiviral Antiviral dose
Adour et al22 1996 United States RCT (double blind) 46 53 Prednisolone oral 1 mg/kg/day for 5 days followed by taper to 10 mg/kg/day over 5 days Aciclovir 2000 mg/day for 10 days
Hato et al12 2007 Japan RCT (single blind) 107 114 Prednisolone oral 60 mg/day for 5 days, 30 mg/day for 3 days, 10 mg/day for 2 days Valaciclovir 1000 mg/day for 5 days
Sullivan et al6 2007 United Kingdom RCT (double blind) 127 124 Prednisolone oral 50 mg/day for 10 days Aciclovir 2000 mg/day for 10 days
Engstrom et al14 2008 Sweden RCT (double blind) 180 186 Prednisolone oral 60 mg/day for 5 days, 50 mg/day for 1 day, 40 mg/day for 1 day, 30 mg/day for 1 day, 20 mg/day for 1 day, 10 mg/day for 1 day Valaciclovir 3000 mg/day for 7 days
Minnerop et al9 2008 Germany RCT (not blinded) 67 50 Prednisone oral 1 mg/kg/day for 4 days, taper over 8 days Famciclovir 250 mg/day for 7 days
Yeo et al10 2008 South Korea RCT (double blind) 47 44 Prednisolone oral 1 mg/kg/day for 4 days, 60 mg/kg/day for 2 days, 40 mg/kg/day for 2 days, 20 mg/kg/day for 2 days Aciclovir 2400 mg/day for 5 days

RCT, randomised controlled trial.